AKAP13
Once upon a time, in a gene so grand,
Lived a protein called AKAP-Lbc, oh so grand.
It had a special power, you see,
To encode the Lbc oncogene, how fancy!
AKAP-Lbc, a name quite long,
But it had a purpose, oh so strong.
In humans, it played a vital role,
In the lymphocyte blast crisis, a story to unfold.
But wait, there's more to this protein tale,
ARHGEF13, another name to unveil.
For AKAP-Lbc had a secret domain,
A guanine nucleotide exchange factor, how insane!
This domain, you see, had a special task,
To interact with RhoA, a protein in its class.
It helped RhoA to bind and exchange,
Guanine nucleotides, a biochemical exchange.
So let us remember AKAP-Lbc's story,
A protein with names, both grand and gory.
It encoded the Lbc oncogene, oh so clever,
And had a domain for RhoA, a protein to treasure.
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