AY 61122
In the land of veterinary medicine,
There was a magical potion, so serene.
Metallibure was its name, oh so grand,
Introduced in 1973, across the land.
With brand names like Aimax and Turisynchron,
It helped synchronize estrus, oh what fun!
But alas, in the US and Europe, it was withdrawn,
Due to teratogenicity, it was gone.
Its mechanism of action, a mystery untold,
A nonsteroidal antigonadotropin, we're told.
Acting on the pituitary gland, or maybe the hypothalamus,
Suppressing gonadotropin secretion, oh what a fuss!
But wait, there's more to this magical potion,
It's also an antiprogestogen, causing commotion.
Inhibiting progesterone, its power is great,
But with side effects, we must be cautious, mate.
For women, it has endocrinological effects,
With appetite loss and nausea, it connects.
Lethargy and drowsiness, it may bring,
And cataracts in animals, a troubling thing.
So let us remember the tale of Metallibure,
A magical potion, with effects obscure.
Though it's no longer used, its story we'll share,
In the land of veterinary medicine, with care.
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