BB-Homodimer

In our bodies, a power resides, Platelet-derived growth factor, it hides. Regulating growth and division, you see, A key player in our biology. Blood vessels, it helps to form, From existing tissue, it will transform. Mesenchymal cells, it will make grow, Fibroblasts, osteoblasts, and more in tow. Chemotaxis, it knows the way, Guiding cells where they need to stay. Mesenchymal cells, they migrate, Following PDGF, they navigate. A dimeric glycoprotein, it's true, Composed of subunits, one or two. PDGF-AA, PDGF-BB, or PDGF-AB, Together they form this growth factor, you see. In our bodies, it's a potent mitogen, For fibroblasts, smooth muscle, and glial cells, again. A network of ligands and receptors, it has, PDGF-AA through -DD, a growth factor jazz. Stored in platelets, it's released when they activate, But other cells also produce it, don't hesitate. Smooth muscle cells, macrophages, and endothelial too, All contribute to the PDGF brew. In medicine, it's used to heal, Chronic ulcers, it can reveal. In orthopedic surgery, it plays a part, Stimulating bone regeneration, a healing art. So let's celebrate platelets, so small but strong, With PDGF, they help our bodies along. A power hidden within, so grand, Platelet-derived growth factor, a wonderland. Random page: KUFO (disambiguation)