HBGF1

In a world of proteins, so grand and vast, There's one called FGF-1, a growth factor that lasts. It's encoded by FGF1, a gene so fine, Creating a protein that's simply divine. A polypeptide, with 155 amino acids so neat, Matures into a protein, small and sweet. Non-glycosylated, it weighs 17-18 kDa, FGF-1, oh how it likes to play! Discovered in 1975, purified with care, FGF-1, a protein beyond compare. Others found it too, under different names, Acidic FGF, Heparin-binding, all part of the game. No signal sequence, it's not secreted the usual way, Instead, it forms a dimer, ready to play. With proteins at the cell membrane, it takes flight, Flipping through the membrane, oh what a sight! Once in the tissue, it dissociates with glee, Becoming monomeric, setting itself free. Binding to heparan sulfate proteoglycans with grace, FGF-1, exploring the extracellular space. So remember, little ones, the tale of FGF-1, A whimsical protein, full of fun. It binds to receptors, both outside and in, A growth factor's journey, a magical spin. Random page: Dna melting