LYRM7
In the mitochondria, a protein so fine,
LYRM7 is its name, oh how it shines!
It stabilizes UQCRFS1, so grand,
And chaperones it to the CIII complex, hand in hand.
A nuclear-encoded mitochondrial mate,
LYRM7 helps keep the energy state.
It's a matrix protein, inside the cell,
Working hard to keep the mitochondria well.
Mitochondrial complex III deficiency, it can cause,
But LYRM7 is here, with its helpful applause.
Defects in this gene, a challenge to face,
But LYRM7 is there, a saving grace.
Transcript variants, not just one, but three,
Different isoforms, oh how can it be?
LYRM7 gene, a wondrous sight,
Variety and diversity, shining so bright.
So let's celebrate LYRM7, with a cheer,
For its role in the mitochondria, so clear.
A protein that chaperones and stabilizes with care,
LYRM7, oh how we're grateful you're there!
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GRAMMYs On The Hill 2018