LY 451395
In a lab, so bright and clean,
Mibampator was a dream.
A special potion, they did brew,
To help with Alzheimer's, it's true.
Mibampator, a modulator grand,
On AMPA receptors it did land.
It boosted signals, oh so strong,
To help with memory, all day long.
In animals, it showed great might,
Enhancing cognition, oh what a sight!
But at higher doses, it caused a fuss,
With disruptions and convulsions, oh woe to us!
In patients with Alzheimer's, it was tried,
But cognitive improvement, it couldn't provide.
Neuropsychiatric measures, it did enhance,
But toxicity stopped it from its full chance.
Mibampator, a melody untold,
A hopeful story, yet not as bold.
Though it didn't succeed as they had planned,
Its journey in the lab will always stand.
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Kn toosi university of technology