PrFMNiminium
In the land of enzymes, oh so grand,
There's a cofactor, you must understand,
Prenylated flavin mononucleotide, you see,
Biosynthesized by UbiX, a magical key.
UbiD enzymes, they use it well,
For reversible decarboxylation, a magical spell,
Catalysis they perform, with prFMN in hand,
In the UbiD/X system, across the land.
Flavin prenylated, at positions N5 and C6,
A fourth non-aromatic ring, a magical mix,
Discovered in Manchester, by David Leys' group,
In 2015, they made this magical loop.
UbiX, a prenyltransferase, they found,
Supplying prFMN, all around,
UbiD/Fdc1, they work together,
In a reversible decarboxylation endeavor.
AnFdc1UbiX, a duo so fine,
Purified and ready, like a sparkling wine,
In vitro decarboxylation, they can do,
With a range of aromatic acids, it's true.
The crystal structure, oh so clear,
Revealed the secrets, we hold dear,
Isopentenyl-adduct, to N5-C6 it binds,
Prenylation, a magical find.
So let's celebrate the prenylated flavin,
A cofactor that helps enzymes in their haven,
In the world of science, it's a wondrous thing,
A magical molecule that makes hearts sing.
Random page:
IA, the Journal of the Society for Industrial Archeology