TFAP2C (gene)
In the world of genes, there's one quite grand,
AP-2 Gamma, a protein so grand.
It helps in shaping us, right from the start,
Morphogenesis, it plays a part.
With a special code, it binds so tight,
5'-GCCNNNGGC-3', it's just right.
Interacting with components, both viral and cell,
Regulating genes, oh, it does it so well.
Placenta development, it does activate,
Genes for eyes, face, and limbs, it does create.
Retinoic acid, it helps differentiate,
Making sure our bodies are just great.
MYC and C/EBP alpha, it does suppress,
Keeping them in check, oh, what a success.
CD44 expression, it represses with pride,
Fighting breast and prostate cancers, side by side.
But if AP-2 Gamma goes astray,
Branchiooculofacial syndrome may come our way.
Cleft lip or anophthalmia, what a sight,
Let's keep AP-2 Gamma shining bright.
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TJ Grant